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Malaria in Cambodia: Zero Deaths, But Not Yet Eradicated

The country has eliminated a deadly strain and recorded no deaths for years. What this means for expats.

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Updated 2026-04-28 5 min

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In short

  • Cambodia has recorded no malaria deaths for several years.
  • A deadly strain of malaria has been eliminated from the country.
  • Cases are at historic lows, but malaria persists in some rural and forested areas.
  • For expats in Siem Reap, the risk is very low, but prevention is still recommended if traveling to rural areas.
0 for several years
Malaria deaths
Multidrug-resistant P. falciparum
Eliminated strain
Historic low
Annual cases
Very low
Risk in Siem Reap

What exactly happened?

Cambodia has achieved a major milestone in the fight against malaria. According to health authorities and the WHO, the country has recorded no malaria-related deaths for several years. Moreover, a particularly dangerous strain of Plasmodium falciparum, resistant to treatment, has been officially eliminated from the territory.

Malaria cases are now at historic lows. This success is the result of prevention campaigns, distribution of mosquito nets, and increased access to treatment. Cambodia now aims for WHO 'malaria-free' certification, a process that requires a few more years without local transmission.

What this means for you in Siem Reap

For expats and travelers living in Siem Reap, the risk of contracting malaria is very low. The city and its immediate surroundings are not considered high-risk areas. Reported cases mainly involve remote rural areas, especially near the Thai and Lao borders, and forested regions.

If you live in Siem Reap and do not travel to these areas, you do not need routine preventive treatment. However, if you plan jungle excursions or extended stays in rural areas, a medical consultation to assess the need for prophylaxis is recommended.

What to do if you are concerned

Here are practical steps to take:

  • Before traveling to a rural area: consult a doctor or a tropical medicine clinic in Siem Reap (e.g., Angkor Hospital for Children or Sihanouk Clinic). Ask if antimalarial prophylaxis is necessary based on your itinerary.
  • During your stay in a risk area: use mosquito repellent containing DEET, sleep under an impregnated mosquito net, and wear long clothing in the evening.
  • If symptoms occur: fever, chills, headache — seek medical attention promptly. Malaria is treatable if caught early. Rapid diagnostic tests are available at most clinics.
  • In Siem Reap itself: no special daily precautions needed. Mosquitoes are more of a nuisance than a major health risk.

Common pitfalls to avoid

First pitfall: believing malaria has completely disappeared. It hasn't. Zero risk does not exist, especially if you venture into forested areas of Mondulkiri, Ratanakiri provinces, or near the Thai border.

Second pitfall: dismissing symptoms as flu or dengue. Dengue is also present in Cambodia and can cause similar symptoms. A blood test is the only way to differentiate.

Third pitfall: relying on unofficial information. Some expat forums may downplay or exaggerate the risk. Refer to WHO and Cambodian Ministry of Health recommendations.

What to watch for in the coming weeks

Cambodia is expected to submit its certification dossier to the WHO in the coming months. If certification is granted, it will further boost the country's appeal for health-conscious expats and travelers.

In the meantime, epidemiological surveillance continues. Authorities remain vigilant against possible reintroduction of the parasite via travelers from neighboring countries where malaria still circulates.

For expats, the positive trend is good news: it confirms that health infrastructure and prevention policies are effective. Stay informed through official channels and local clinics.

Frequently asked questions

Should I take preventive malaria medication if I live in Siem Reap?
No, it is not recommended for Siem Reap residents. The risk is very low. Prophylaxis is only advised if you travel to high-risk rural areas, such as Mondulkiri or Ratanakiri provinces.
Where can I get tested for malaria in Siem Reap?
Several clinics and hospitals offer rapid diagnostic tests, including Angkor Hospital for Children, Sihanouk Clinic, and Royal Angkor International Hospital. The test is simple and results are available in 15 to 30 minutes.
Is malaria resistant to treatment in Cambodia?
The multidrug-resistant strain of Plasmodium falciparum has been eliminated. Current treatments, especially artemisinin-based combination therapies, remain effective against the strains still present.
Are there other mosquito-borne diseases in Siem Reap?
Yes, dengue is present year-round, with peaks during the rainy season. Chikungunya and Zika virus are also reported, but less frequently. The same mosquito bite prevention measures are recommended.

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Siem Reap Hub

The community guide for expats and travelers in Siem Reap, Cambodia